Semaglutide
Compounded Semaglutide is a once-weekly injection that reduces cravings and appetite, leading to weight loss. It also helps regulate blood sugar and increases insulin secretion, which can boost metabolic health. Now approved by the FDA.
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How to Compare Injectable Weight Loss Drugs
You may have heard the buzz about injectable medicines that many people are now using to help them lose weight and wondered if one of them could be right for you. Reaching and sticking to a healthy weight can be hard, but it does come with many health benefits. It can lower your chances of diabetes, heart disease, some cancers, sleep apnea, and many other health conditions.
While diet and exercise alone may get you there, these weight loss drugs can be a new lease on life for people who have diabetes or obesity. But you also may have lots of questions including whether they really work and how. You might also wonder how these medications – including Mounjaro, Ozempic, Wegovy, and Zepbound – compare to each other and why you might choose one over another.
These drugs do have a lot of similarities but also important differences. For example, all of them include a class of drug that’s known as a GLP-1 agonist. An agonist is a drug that works by acting like a substance that your body naturally has. GLP-1 stands for glucagon-like peptide 1, which is a hormone your small intestine makes. When blood sugar goes up, GLP-1 encourages your body to make more insulin to lower blood sugar. These drugs do the same thing.
How do GLP-1 agonists help with weight loss? They may make you feel less hungry by keeping any food you eat in your GI tract for longer. This makes it take longer for you to feel hungry again after a meal, so it’s easier to eat less. They may also send signals to your brain that tell it that you’re feeling full.
Of course, like any drug, these medicines do have downsides. They can come with side effects, including nausea. They’re costly and may not be covered by health insurance. You may need to take them indefinitely to maintain your weight unless you make other lifestyle changes. And because they’re relatively new, it’s not yet clear how they will affect your health over many years.
Because of all this, it’s a good idea to talk to your doctor if you think you might like to try one of these to lose weight and improve your health. It will help to learn all you can up-front before you decide to give any of these new drugs a try. Make sure you have all your questions answered so you can make an informed choice that’s right for you.
Semaglutide vs. tirzepatide
Semaglutide is the active ingredient in Ozempic and Wegovy. It works as a GLP-1 receptor agonist to treat type 2 diabetes. People also use it to help them lose weight. Tirzepatide is the active ingredient in Mounjaro and Zepbound, which also can treat type 2 diabetes and encourage weight loss. Tirzepatide is a GLP-1 receptor agonist, too. But it also works in a second way, as what’s known as a GIP receptor agonist. GIP, short for glucose-dependent insulinotropic polypeptide, is another hormone your body makes after you eat.
So both semaglutide and tirzepatide work by acting like hormones your body normally makes after you eat. They can make your stomach empty more slowly so that you won’t want to eat again as soon. They also send signals to the brain that tell you you’re full. The main difference is that tirzepatide mimics two hormones while semaglutide mimics one.
Takeaways
Mounjaro, Ozempic, Wegovy, and Zepbound are all relatively new weight loss drugs. They both work to slow down your stomach and GI tract. They also can send signals to your brain that help you feel full longer and eat less. While some of them are only approved as treatments for type 2 diabetes, all of them can make people lose weight. Talk to your doctor about whether they recommend you try an injectable weight loss drug along with diet and exercise to improve your health.
